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Age-related brain structural alterations as an intermediate phenotype of psychosis
Author(s) -
Juergen Dukart,
Renata Smieskova,
Fabienne Harrisberger,
Claudia Lenz,
André Schmidt,
Anna Walter,
Christian G. Huber,
Anita RiecherRössler,
Andor E. Simon,
Undine E. Lang,
Paolo FusarPoli,
Stefan Borgwardt
Publication year - 2017
Publication title -
journal of psychiatry and neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.767
H-Index - 99
eISSN - 1488-2434
pISSN - 1180-4882
DOI - 10.1503/jpn.160179
Subject(s) - psychosis , grey matter , young adult , schizophrenia (object oriented programming) , voxel , psychology , voxel based morphometry , medicine , psychiatry , clinical psychology , magnetic resonance imaging , white matter , radiology
There is only limited agreement with respect to location, directionality and functional implications of brain structural alterations observed in patients with schizophrenia. Additionally, their link to occurrence of psychotic symptoms remains unclear. A viable way of addressing these questions is to examine populations in an at-risk mental state (ARMS) before the transition to psychosis.

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