Cortical morphology as a shared neurobiological substrate of attention-deficit/hyperactivity symptoms and executive functioning: a population-based pediatric neuroimaging study | Zendy

Sabine E. Mous | Zendy; Tonya White | Zendy; Ryan L. Muetzel | Zendy; Hanan El Marroun | Zendy; JolienQ Rijlaarsdam | Zendy; Tinca J. C. Polderman | Zendy; Vincent W. V. Jaddoe | Zendy; Frank C. Verhulst | Zendy; Daniëlle Posthuma | Zendy; Henning Tiemeier | Zendy

Open Access

Cortical morphology as a shared neurobiological substrate of attention-deficit/hyperactivity symptoms and executive functioning: a population-based pediatric neuroimaging study

Author(s) -

Sabine E. Mous,

Tonya White,

Ryan L. Muetzel,

Hanan El Marroun,

JolienQ Rijlaarsdam,

Tinca J. C. Polderman,

Vincent W. V. Jaddoe,

Frank C. Verhulst,

Daniëlle Posthuma,

Henning Tiemeier

Publication year - 2017

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.150371

Subject(s) - attention deficit hyperactivity disorder , gyrification , neuroimaging , cognition , psychology , population , brain morphometry , cognitive deficit , neurocognitive , executive functions , psychiatry , clinical psychology , neuroscience , medicine , magnetic resonance imaging , cognitive impairment , cerebral cortex , environmental health , radiology

Attention-deficit/hyperactivity symptoms have repeatedly been associated with poor cognitive functioning. Genetic studies have demonstrated a shared etiology of attention-deficit/hyperactivity disorder (ADHD) and cognitive ability, suggesting a common underlying neurobiology of ADHD and cognition. Further, neuroimaging studies suggest that altered cortical development is related to ADHD. In a large population-based sample we investigated whether cortical morphology, as a potential neurobiological substrate, underlies the association between attention-deficit/hyperactivity symptoms and cognitive problems.

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