Dopamine effects on evidence gathering and integration | Zendy

Christina Andreou | Zendy; Brooke C. Schneider | Zendy; Vivien Braun | Zendy; Katharina Kolbeck | Zendy; Jürgen Gallinat | Zendy; Steffen Moritz | Zendy

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Dopamine effects on evidence gathering and integration

Author(s) -

Christina Andreou,

Brooke C. Schneider,

Vivien Braun,

Katharina Kolbeck,

Jürgen Gallinat,

Steffen Moritz

Publication year - 2015

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.140306

Subject(s) - haloperidol , dopaminergic , psychology , placebo , antipsychotic , dopamine , developmental psychology , neuroscience , psychiatry , medicine , schizophrenia (object oriented programming) , alternative medicine , pathology

Disturbances in evidence gathering and disconfirmatory evidence integration have been associated with the presence of or propensity for delusions. Previous evidence suggests that these 2 types of reasoning bias might be differentially affected by antipsychotic medication. We aimed to investigate the effects of a dopaminergic agonist (L-dopa) and a dopaminergic antagonist (haloperidol) on evidence gathering and disconfirmatory evidence integration after single-dose administration in healthy individuals.

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