White matter tractography in early psychosis: clinical and neurocognitive associations
Author(s) -
Sean N. Hatton,
Jim Lagopoulos,
Daniel F. Hermens,
Ian B. Hickie,
Elizabeth Scott,
Maxwell R. Bennett
Publication year - 2014
Publication title -
journal of psychiatry and neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.767
H-Index - 99
eISSN - 1488-2434
pISSN - 1180-4882
DOI - 10.1503/jpn.130280
Subject(s) - inferior longitudinal fasciculus , psychosis , white matter , neurocognitive , fractional anisotropy , psychology , diffusion mri , psychiatry , superior longitudinal fasciculus , fornix , neuropsychology , medicine , clinical psychology , neuroscience , cognition , magnetic resonance imaging , hippocampus , radiology
While many diffusion tensor imaging (DTI) investigations have noted disruptions to white matter integrity in individuals with chronic psychotic disorders, fewer studies have been conducted in young people at the early stages of disease onset. Using whole tract reconstruction techniques, the aim of this study was to identify the white matter pathology associated with the common clinical symptoms and executive function impairments observed in young people with psychosis.
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