Brain grey matter volume alterations in late-life depression
Author(s) -
Mingying Du,
Jia Liu,
Ziqi Chen,
Xiaoqi Huang,
Jing Li,
Weihong Kuang,
Yanchun Yang,
Wei Zhang,
Dong Zhou,
Feng Bi,
Keith M. Kendrick,
Qiyong Gong
Publication year - 2014
Publication title -
journal of psychiatry and neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.767
H-Index - 99
eISSN - 1488-2434
pISSN - 1180-4882
DOI - 10.1503/jpn.130275
Subject(s) - grey matter , voxel based morphometry , meta analysis , voxel , psychology , medicine , magnetic resonance imaging , neuroscience , pathology , white matter , radiology
Voxel-based morphometry (VBM) studies have demonstrated that grey matter abnormalities are involved in the pathophysiology of late-life depression (LLD), but the findings are inconsistent and have not been quantitatively reviewed. The aim of the present study was to conduct a meta-analysis that integrated the reported VBM studies, to determine consistent grey matter alterations in individuals with LLD.
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