Impact of acute administration of escitalopram on the processing of emotional and neutral images: a randomized crossover fMRI study of healthy women | Zendy

Tim Outhred | Zendy; Pritha Das | Zendy; Kim L. Felmingham | Zendy; Richard A. Bryant | Zendy; Pradeep J. Nathan | Zendy; Gin S. Malhi | Zendy; Andrew H. Kemp | Zendy

Open Access

Impact of acute administration of escitalopram on the processing of emotional and neutral images: a randomized crossover fMRI study of healthy women

Author(s) -

Tim Outhred,

Pritha Das,

Kim L. Felmingham,

Richard A. Bryant,

Pradeep J. Nathan,

Gin S. Malhi,

Andrew H. Kemp

Publication year - 2014

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.130118

Subject(s) - escitalopram , psychology , serotonin reuptake inhibitor , citalopram , randomized controlled trial , crossover study , placebo , antidepressant , amygdala , audiology , medicine , psychiatry , clinical psychology , neuroscience , anxiety , alternative medicine , pathology

Acute neural effects of antidepressant medication on emotion processing biases may provide the foundation on which clinical outcomes are based. Along with effects on positive and negative stimuli, acute effects on neutral stimuli may also relate to antidepressant efficacy, yet these effects are still to be investigated. The present study therefore examined the impact of a single dose of the selective serotonin reuptake inhibitor escitalopram (20 mg) on positive, negative and neutral stimuli using pharmaco-fMRI.

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