COMT, neuropsychological function and brain structure in schizophrenia: a systematic review and neurobiological interpretation | Zendy

Elisa Ira | Zendy; Martina Zai | Zendy; Mirella Ruggeri | Zendy; Paola Dazzan | Zendy; Sarah Tosato | Zendy

Open Access

COMT, neuropsychological function and brain structure in schizophrenia: a systematic review and neurobiological interpretation

Author(s) -

Elisa Ira,

Martina Zai,

Mirella Ruggeri,

Paola Dazzan,

Sarah Tosato

Publication year - 2013

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.120178

Subject(s) - neuropsychology , schizophrenia (object oriented programming) , psychology , brain function , interpretation (philosophy) , brain structure and function , neuroscience , cognitive psychology , neuroimaging , clinical psychology , cognition , psychiatry , philosophy , linguistics

Endophenotypes in genetic psychiatry may increase our understanding of the molecular mechanisms underlying disease risk and its manifestations. We sought to investigate the link between neuropsychological impairments and brain structural abnormalities associated with the COMT Val(158)Met polymorphism in patients with schizophrenia to improve understanding of the pathophysiology of this disorder.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research