Searching for an endogenous anti-Alzheimer molecule: identifying small molecules in the brain that slow Alzheimer disease progression by inhibition of β-amyloid aggregation | Zendy

Autumn Meek | Zendy; Gordon A. Simms | Zendy; Donald F. Weaver | Zendy

Open Access

Searching for an endogenous anti-Alzheimer molecule: identifying small molecules in the brain that slow Alzheimer disease progression by inhibition of β-amyloid aggregation

Author(s) -

Autumn Meek,

Gordon A. Simms,

Donald F. Weaver

Publication year - 2013

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.120166

Subject(s) - amyloid (mycology) , endogeny , neurotoxicity , chemistry , in silico , biochemistry , in vitro , in vivo , alzheimer's disease , human brain , small molecule , pharmacology , biology , neuroscience , medicine , toxicity , disease , inorganic chemistry , microbiology and biotechnology , organic chemistry , gene

Alzheimer disease is a neurodegenerative disorder that progresses with marked interindividual clinical variability. We postulate the existence of endogenous molecules within the human brain exerting an antiaggregant activity that will prevent/slow Alzheimer disease progression.

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