Atypical coupling between posterior regions of the default mode network in attention-deficit/hyperactivity disorder: a pharmaco-magnetoencephalography study | Zendy

John D. Franzen | Zendy; Elizabeth HeinrichsGraham | Zendy; Matthew L. White | Zendy; Martin W. Wetzel | Zendy; Nichole L. Knott | Zendy; Tony W. Wilson | Zendy

Open Access

Atypical coupling between posterior regions of the default mode network in attention-deficit/hyperactivity disorder: a pharmaco-magnetoencephalography study

Author(s) -

John D. Franzen,

Elizabeth HeinrichsGraham,

Matthew L. White,

Martin W. Wetzel,

Nichole L. Knott,

Tony W. Wilson

Publication year - 2013

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.120054

Subject(s) - magnetoencephalography , default mode network , attention deficit hyperactivity disorder , neuroscience , psychology , magnetic resonance imaging , neuroimaging , coupling (piping) , medicine , psychiatry , functional connectivity , electroencephalography , radiology , mechanical engineering , engineering

Dysfunction in the default mode network (DMN), a group of cortical areas more active during the resting state, has been linked to attentional deficits and symptoms associated with attention-deficit/hyperactivity disorder (ADHD). Prior imaging studies have shown decreased functional connectivity between DMN nodes in patients with ADHD, primarily between anterior and posterior regions. Using magnetoencephalography (MEG), we evaluated phase coherence (i.e., functional connectivity) among regions of the DMN in healthy controls and adults with ADHD before and after stimulant therapy.

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