Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosa | Zendy

Laura M. Holsen | Zendy; Elizabeth A. Lawson | Zendy; Justine Blum | Zendy; Eunice Ko | Zendy; Nikos Makris | Zendy; Pouneh K. Fazeli | Zendy; Anne Klibanski | Zendy; Jill M. Goldstein | Zendy

Open Access

Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosa

Author(s) -

Laura M. Holsen,

Elizabeth A. Lawson,

Justine Blum,

Eunice Ko,

Nikos Makris,

Pouneh K. Fazeli,

Anne Klibanski,

Jill M. Goldstein

Publication year - 2012

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.110156

Subject(s) - anorexia nervosa , appetite , psychology , insula , medicine , endocrinology , eating disorders , psychiatry , neuroscience

Previous studies have provided evidence of food motivation circuitry dysfunction in individuals with anorexia nervosa. However, methodological limitations present challenges to the development of a cohesive neurobiological model of anorexia nervosa. Our goal was to investigate the neural circuitry of appetite dysregulation across states of hunger and satiety in active and weight-restored phases of anorexia nervosa using robust methodology to advance our understanding of potential neural circuitry abnormalities related to hedonic and nonhedonic state and trait.

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