Smaller hippocampal volumes in patients with bipolar disorder are masked by exposure to lithium: a meta-analysis | Zendy

Tomáš Hájek | Zendy; Miloslav Kopeček | Zendy; Cyril Höschl | Zendy; Martin Alda | Zendy

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Smaller hippocampal volumes in patients with bipolar disorder are masked by exposure to lithium: a meta-analysis

Author(s) -

Tomáš Hájek,

Miloslav Kopeček,

Cyril Höschl,

Martin Alda

Publication year - 2012

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.110143

Subject(s) - hippocampal formation , bipolar disorder , neuroimaging , lithium (medication) , confidence interval , meta analysis , medicine , psychology , hippocampus , depression (economics) , cardiology , psychiatry , economics , macroeconomics

Smaller hippocampal volumes relative to controls are among the most replicated neuroimaging findings in individuals with unipolar but not bipolar depression. Preserved hippocampal volumes in most studies of participants with bipolar disorder may reflect potential neuroprotective effects of lithium (Li).

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