Differential effects of 3 classes of antidiabetic drugs on olanzapine-induced glucose dysregulation and insulin resistance in female rats | Zendy

Heidi N. Boyda | Zendy; Ric M. Procyshyn | Zendy; Lurdes Tse | Zendy; Erin Hawkes | Zendy; Jin Chen | Zendy; Catherine C.Y. Pang | Zendy; William G. Honer | Zendy; Alasdair M. Barr | Zendy

Open Access

Differential effects of 3 classes of antidiabetic drugs on olanzapine-induced glucose dysregulation and insulin resistance in female rats

Author(s) -

Heidi N. Boyda,

Ric M. Procyshyn,

Lurdes Tse,

Erin Hawkes,

Jin Chen,

Catherine C.Y. Pang,

William G. Honer,

Alasdair M. Barr

Publication year - 2012

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.110140

Subject(s) - olanzapine , rosiglitazone , metformin , insulin resistance , endocrinology , medicine , insulin , antipsychotic , atypical antipsychotic , glucose tolerance test , diabetes mellitus , glucose homeostasis , carbohydrate metabolism , pharmacology , type 2 diabetes , schizophrenia (object oriented programming) , psychiatry

The second-generation antipsychotic drug olanzapine is an effective pharmacological treatment for psychosis. However, use of the drug is commonly associated with a range of metabolic side effects, including glucose intolerance and insulin resistance. These symptoms have been accurately modelled in rodents.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research