Impaired interhemispheric connectivity in medicationnaive patients with major depressive disorder
Author(s) -
Ke Xu,
Wenyan Jiang,
Ling Ren,
Xuan Ouyang,
Yifeng Jiang,
Feng Wu,
Lingtao Kong,
Fay Y. Womer,
Zhening Liu,
Hilary P. Blumberg,
Yanqing Tang,
Fei Wang
Publication year - 2012
Publication title -
journal of psychiatry and neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.767
H-Index - 99
eISSN - 1488-2434
pISSN - 1180-4882
DOI - 10.1503/jpn.110132
Subject(s) - fractional anisotropy , major depressive disorder , corpus callosum , diffusion mri , psychology , medicine , neuroscience , magnetic resonance imaging , psychiatry , radiology , amygdala
Abnormalities in the anterior interhemispheric connections provided by the corpus callosum (CC) have long been implicated in major depressive disorder (MDD). The purpose of this study was to investigate interhemispheric connectivity in medication-naive patients with MDD by measuring fractional anisotropy in the CC with diffusion tensor imaging (DTI) techniques.
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