Differential association between the norepinephrine transporter gene and ADHD: role of sex and subtype | Zendy

Sarojini M. Sengupta | Zendy; Natalie Grizenko | Zendy; Geeta A. Thakur | Zendy; Johanne Bellingham | Zendy; Rosherrie DeGuzman | Zendy; Sandra Robinson | Zendy; Marina Ter-Stepanian | Zendy; Anna Poloskia | Zendy; S.M. Shaheen | Zendy; MarieÈve Fortier | Zendy; Zia Choudhry | Zendy; Ridha Joober | Zendy

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Differential association between the norepinephrine transporter gene and ADHD: role of sex and subtype

Author(s) -

Sarojini M. Sengupta,

Natalie Grizenko,

Geeta A. Thakur,

Johanne Bellingham,

Rosherrie DeGuzman,

Sandra Robinson,

Marina Ter-Stepanian,

Anna Poloskia,

S.M. Shaheen,

MarieÈve Fortier,

Zia Choudhry,

Ridha Joober

Publication year - 2012

Publication title -

journal of psychiatry and neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.767

H-Index - 99

eISSN - 1488-2434

pISSN - 1180-4882

DOI - 10.1503/jpn.110073

Subject(s) - haplotype , single nucleotide polymorphism , norepinephrine transporter , attention deficit hyperactivity disorder , genetics , genetic association , biology , snp , candidate gene , bonferroni correction , phenotype , gene , genotype , psychology , clinical psychology , transporter , statistics , mathematics

Pharmacologic and animal studies have strongly implicated the norepinephrine transporter (NET) in the pathophysiology of attention-deficit/hyperactivity disorder (ADHD). We conducted a family-based study, with stratification based on sex and subtype, to test the association between 30 tag single-nucleotide polymorphisms (SNPs) within the gene encoding NET (SLC6A2) and ADHD.

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