Combined analysis of grey matter voxel-based morphometry and white matter tract-based spatial statistics in late-life bipolar disorder
Author(s) -
Sven Haller,
Aikaterini Xekardaki,
Christophe Delaloye,
Alessandra Canuto,
KarlOlof Lövblad,
Garry E. Gold,
Pantèleimon Giannakopoulos
Publication year - 2011
Publication title -
journal of psychiatry and neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.767
H-Index - 99
eISSN - 1488-2434
pISSN - 1180-4882
DOI - 10.1503/jpn.100140
Subject(s) - fractional anisotropy , corpus callosum , white matter , grey matter , bipolar disorder , diffusion mri , anterior cingulate cortex , psychology , bipolar i disorder , magnetic resonance imaging , medicine , neuroscience , psychiatry , mania , radiology , mood , cognition
Previous magnetic resonance imaging (MRI) studies in young patients with bipolar disorder indicated the presence of grey matter concentration changes as well as microstructural alterations in white matter in various neocortical areas and the corpus callosum. Whether these structural changes are also present in elderly patients with bipolar disorder with long-lasting clinical evolution remains unclear.
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