Lynch syndrome in a predominantly Afrocentric population: a clinicopathological and genetic study
Author(s) -
Joseph M. Plummer,
Sheray N. Chin,
Melyssa Aronson,
Rondell P. Graham,
Nadia P. Williams,
Bharati Bapat,
Gillian Wharfe,
Aaron Pollett,
Steven Gallinger
Publication year - 2012
Publication title -
canadian journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.609
H-Index - 64
eISSN - 1488-2310
pISSN - 0008-428X
DOI - 10.1503/cjs.037410
Subject(s) - lynch syndrome , medicine , microsatellite instability , mlh1 , colorectal cancer , population , histopathology , germline mutation , dna mismatch repair , gastroenterology , pathology , cancer , msh2 , oncology , mutation , genetics , microsatellite , gene , biology , allele , environmental health
We investigated the prevalence of Lynch syndrome as a hereditary cause of colon cancer in the young Jamaican colorectal cancer (CRC) population.
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