Effects of trimetazidine in acute pancreatitis induced by L-arginine
Author(s) -
Akan Yeniçerioğlu,
Ziya Çetinkaya,
Mustafa Gırgın,
Bilal Üstündağ,
İbrahim H. Özercan,
Refik Ayten,
Burhan Hakan Kanat
Publication year - 2013
Publication title -
canadian journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.609
H-Index - 64
eISSN - 1488-2310
pISSN - 0008-428X
DOI - 10.1503/cjs.032811
Subject(s) - medicine , acute pancreatitis , trimetazidine , pancreatitis , endocrinology , edema , necrosis , microcirculation , lactate dehydrogenase , pancreatic injury , amylase , inflammation , systemic inflammation , gastroenterology , enzyme , biochemistry , chemistry
In acute pancreatitis, oxygen free radicals (OFRs) and cytokines have been shown to play a role in the failure of pancreatic microcirculation and the development of local tissue damage. We studied the effects of trimetazidine (TMZ), a potent antioxidant and anti-ischemic agent, on acute pancreatitis.
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