Differences in telomerase activity between colon and rectal cancer | Zendy

Georgios Ayiomamitis | Zendy; George Notas | Zendy; Apostolos Zaravinos | Zendy; Adamantia Zizi-Sermpetzoglou | Zendy; Μαρία Γεωργιάδου | Zendy; Ourania Sfakianaki | Zendy; Elias Kouroumallis | Zendy

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Differences in telomerase activity between colon and rectal cancer

Author(s) -

Georgios Ayiomamitis,

George Notas,

Apostolos Zaravinos,

Adamantia Zizi-Sermpetzoglou,

Μαρία Γεωργιάδου,

Ourania Sfakianaki,

Elias Kouroumallis

Publication year - 2014

Publication title -

canadian journal of surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.609

H-Index - 64

eISSN - 1488-2310

pISSN - 0008-428X

DOI - 10.1503/cjs.031312

Subject(s) - telomerase , colorectal cancer , medicine , mlh1 , cancer , rectum , pathological , pathology , cancer research , oncology , biology , dna mismatch repair , gene , biochemistry

Colorectal cancer is one of the most common cancers and the third leading cause of cancer death in both sexes. The disease progresses as a multistep process and is associated with genetic alterations. One of the characteristic features of cancer is telomerase activation. We sought to evaluate the differences in telomerase activity between colon cancer and adjacent normal tissue and to correlate the differences in telomerase activity between different locations with clinicopathological factors and survival.

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