Tumour budding predicts increased recurrence after curative resection for T2N0 colorectal cancer
Author(s) -
Richard Garfinkle,
Lawrence Lee,
Marylise Boutros,
Marie-Josee Cardin,
Alan Spatz,
Nancy Morin
Publication year - 2019
Publication title -
canadian journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.609
H-Index - 64
eISSN - 1488-2310
pISSN - 0008-428X
DOI - 10.1503/cjs.019017
Subject(s) - medicine , colorectal cancer , hazard ratio , tumor budding , budding , interquartile range , confidence interval , retrospective cohort study , cancer , gastroenterology , oncology , surgery , metastasis , biology , genetics , lymph node metastasis
Tumour budding is defined as the presence of a cluster of fewer than 5 cells along the invasive margin. It may confer a worse prognosis in colorectal cancer, but its importance in pT2N0 colorectal cancer is unknown. This study aimed to determine the prognostic value of tumour budding in pT2N0 colorectal cancer.
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