Colonic perforation with intraluminal stents and bevacizumab in advanced colorectal cancer: retrospective case series and literature review | Zendy

Amal Imbulgoda | Zendy; Anthony R. MacLean | Zendy; J. Heine | Zendy; Sébastien Drolet | Zendy; Michael M. Vickers | Zendy

Open Access

Colonic perforation with intraluminal stents and bevacizumab in advanced colorectal cancer: retrospective case series and literature review

Author(s) -

Amal Imbulgoda,

Anthony R. MacLean,

J. Heine,

Sébastien Drolet,

Michael M. Vickers

Publication year - 2015

Publication title -

canadian journal of surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.609

H-Index - 64

eISSN - 1488-2310

pISSN - 0008-428X

DOI - 10.1503/cjs.013014

Subject(s) - medicine , bevacizumab , folfiri , perforation , colorectal cancer , chemotherapy , surgery , retrospective cohort study , cancer , irinotecan , materials science , punching , metallurgy

Self-expanding metal stents (SEMS) are increasingly used in the treatment of malignant large bowel obstruction in the setting of inoperable colorectal cancer. Perforation is a well-known complication associated with these devices. The addition of the vascular endothelial growth factor inhibitor bevacizumab is suspected to increase the rate, but the extent of the increase is not known.

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