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The relationship between postoperative opioid consumption and the incidence of hypoxemic events following total hip arthroplasty: a post hoc analysis
Author(s) -
Margaret Noyes Essex,
Frédéric Camu,
Alain Borgeat,
P. Arline Salomon,
Sharon Pan,
Raymond Cheung
Publication year - 2020
Publication title -
canadian journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.609
H-Index - 64
eISSN - 1488-2310
pISSN - 0008-428X
DOI - 10.1503/cjs.010519
Subject(s) - medicine , parecoxib , anesthesia , placebo , hypoxemia , morphine , post hoc analysis , opioid , analgesic , alternative medicine , receptor , pathology
Postoperative opioid analgesia may cause respiratory depression. We assessed whether following total hip arthroplasty, placebo-adjusted reductions in morphine consumption at 48 hours with parecoxib (47.0%), propacetamol (35.1%) or parecoxib plus propacetamol (67.9%) translated into a reduction in hypoxemic events.

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