ANGİOGENESİS VE KANSER TEDAVİSİNDE YENİ YAKLAŞIMLAR : ANGIOGENESIS AND NEW ASPECTS OF CANCER CHEMOTHERAPHY | Zendy

Süreyya Ölgen | Zendy; Işıl BIÇAK | Zendy; Doğu Nebioğlu | Zendy

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ANGİOGENESİS VE KANSER TEDAVİSİNDE YENİ YAKLAŞIMLAR : ANGIOGENESIS AND NEW ASPECTS OF CANCER CHEMOTHERAPHY

Author(s) -

Süreyya Ölgen,

Işıl BIÇAK,

Doğu Nebioğlu

Publication year - 2002

Publication title -

ankara universitesi eczacilik fakultesi dergisi

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.144

H-Index - 10

eISSN - 2564-6524

pISSN - 1015-3918

DOI - 10.1501/eczfak_0000000376

Subject(s) - angiogenesis , medicine , cancer , cancer therapy , drug , chemotherapy , cancer research , pharmacology , kinase , cancer treatment , oncology , biology , biochemistry

İn present, the chemotherapy of cancer with available drugs and drug combinations are inefficient and there are no efficient therapy for many type of cancer. Angiogenesis is an exiting and promising area of anti-cancer drug research. This concept has opened the door to a multitude of new approaches and targets for developing anti-cancer therapies. The potential new anti-angio genetic therapies offer the possibility for improved efficacy of available drugs and reduced toxicity. In particular, old drugs such as talidomit and small molecule inhibitors of tumorpromoted angiogenesis are more investigated recently. In addition, thyrosine kinase inhibitors offer an attractive approach to the development of small molecule therapies for inhibiting tumor poliferation and angiogenesis. The relationship between cancer and angiogenesis and the new drugs for inhibition of angiogenesis were discussed within this review.

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