INVESTIGATIONS ON THE EFFECT OF BASE AND SOLVENTS ON THE ELIMINATION OF p-TOLUENE SULPHONYL GROUP IN THE SYNTHESIS OF DEHYDRO ALANINE : p-TOLUEN SÜLFONİL GRUBU ELİMİNASYONU İLE DEHİDROALANİN SENTEZ | Zendy

Síbel Süzen | Zendy

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INVESTIGATIONS ON THE EFFECT OF BASE AND SOLVENTS ON THE ELIMINATION OF p-TOLUENE SULPHONYL GROUP IN THE SYNTHESIS OF DEHYDRO ALANINE : p-TOLUEN SÜLFONİL GRUBU ELİMİNASYONU İLE DEHİDROALANİN SENTEZ

Author(s) -

Síbel Süzen

Publication year - 2001

Publication title -

ankara universitesi eczacilik fakultesi dergisi

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.144

H-Index - 10

eISSN - 2564-6524

pISSN - 1015-3918

DOI - 10.1501/eczfak_0000000352

Subject(s) - toluene , stereochemistry , chemistry , combinatorics , mathematics , organic chemistry

Dehydroamino acids are constitutents of certain peptide antibiotics and represent an important class of compound. Considerable attention has been given recently to the preparation of dehydroaminoacids, particularly of the dehydroalanine unit, which is generally derived from serine derivatives. In this study the conversion of a serine to a dehydroalanine unit using different base and solvents was investigated using N-benzyloxycarbonyl-O-tosyl derivative of serine.

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