Investigation on the Quality of Aspirin Tablets Manufactured in Different Countries, by Applying The Methods Used in Pharmaceutical Technology

Because of its easy availability, cheapness, low toxicity and the less side effects, it is the most commonly used of all analgesics (1, 2, 3, 4). It is reported that serious gastric effects and side effects as tinnutus and sensitivity are observed in patients who have been using aspirin for a long time. The mechanism of bleeding in gastrointestinal tract after administration of an aspirin tablet is quite complicated. The more often occurance of bleeding and erosion after administration of an aspirin tablet, observed in gastrointestinal tract in patients, who have low pH, are attributed to the stomach HC1. Even with the analgesic doses, aspirin inhibits the platelet function in the body and extends the bleeding time (2, 3, 5).