Open AccessEffect of presurgical aerobic exercise on cardiometabolic health 30 days after bariatric surgery
Author(s) -
Gilbertson Nicole M.,
Eichner Natalie Z. M.,
Gaitán Julian M.,
Khurshid Mahnoor,
Rexrode Elizabeth A.,
Kranz Sibylle,
Hallowell Peter T.,
Malin Steven K.
Publication year - 2021
Publication title -
physiological reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.918
H-Index - 39
ISSN - 2051-817X
DOI - 10.14814/phy2.15039
Subject(s) - medicine , cardiorespiratory fitness , adiponectin , aerobic exercise , body mass index , quality of life (healthcare) , anaerobic exercise , surgery , physical therapy , obesity , endocrinology , insulin resistance , nursing
We evaluated the effect of preoperative standard medical care (SC) vs. unsupervised aerobic exercise combined with SC (EX + SC) on cardiometabolic health and quality of life (QoL) 30 days after bariatric surgery. Bariatric patients ( n = 14, age: 42.3 ± 2.5 years, body mass index: 45.1 ± 2.5 kg/m 2 ) were match‐paired to presurgical SC ( n = 7) or EX + SC ( n = 7; walking 30 min/day, 5 day/week, 65–85% HR peak ) for 30 days. Body composition, peak cardiorespiratory fitness (VO 2 peak), QoL, inflammation (adiponectin, leptin, cytokeratin‐18), and a 120 min mixed meal tolerance test was performed to assess aortic waveforms (augmentation index, AIx@75), insulin sensitivity, and glucose total area under the curve (tAUC) at the time of surgery (post‐intervention) and 30 days post‐surgery. EX + SC had significantly higher high molecular weight (HMW) adiponectin ( p = 0.01) and ratio of HMW to total adiponectin ( p = 0.04) than SC at 30 days post‐surgery, although they significantly ( p = 0.006; ES = 1.86) decreased total time spent in moderate to vigorous physical activity (MVPA). SC had a significantly greater increase in VO 2 peak ( p = 0.02; ES = 1.54) and decrease in 120 min AIx@75 ( p = 0.02; ES = 1.78) than EX + SC during the post‐surgical period. The increase in MVPA was associated with a reduction in cytokeratin‐18 ( r = −0.67, p = 0.02). Increased VO 2 peak was associated with increased activity/mobility QoL domain ( r = 0.52, p = 0.05) and decreased 120 min AIx@75 ( r = −0.61, p = 0.03) from surgery to post‐surgery. Preoperative EX + SC did not maintain more favorable cardiometabolic health 30 days post‐operation in this pilot study. However, changes in MVPA appear important for QoL and should be considered in future work.