Severe Joint Pain as a Manifestation of Paraneoplastic Rheumatic Syndrome in a Patient with a Malignant Lymphoma: A Case Report and Review of the Literature

Rheumatic diseases (RD) and malignancies may be connected to each other in different ways. It has previously been shown, that RD can be a primary manifestation of an underlying cancer as a paraneoplastic syndrome (PNS). RD are related with increased incidence of different malignancies due to the characteristic of the disease or as a result of drug therapy, for instance immunosuppressive agents and tumor necrosis factor inhibitors .