1,2,3-Triazoles: Scaffold With Medicinal Significance
Author(s) -
Saqlain Haider,
Mohammad Sarwar Alam,
Hinna Hamid
Publication year - 2014
Publication title -
inflammation and cell signaling
Language(s) - English
Resource type - Journals
ISSN - 2330-7803
DOI - 10.14800/ics.95
Subject(s) - oxytocin , oxytocin receptor , lactation , regeneration (biology) , microrna , bioinformatics , homeostasis , medicine , inflammation , biology , endocrinology , microbiology and biotechnology , pregnancy , genetics , gene
Despite a significant work on 1,2,3-triazoles, continuous efforts are still being made to identify novel heterocyclic compounds with potent bioactivities. This review may help the medicinal chemists to develop new leads possessing 1,2,3-triazoles nucleus with higher efficacy. This review throws light on the detailed synthetic approaches which have been used for the synthesis of triazoles since the early development in the area of triazole chemistry. This has been followed by the in depth analysis of the triazoles with respect to their medicinal significance.
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