Open AccessThe role of oxidative stress in renal injury related to obesity
Author(s) -
Damiana Tortolero Pierine,
Guilherme Augusto Biondo,
Vanessa dos Santos Silva,
Camila Renata Corrêa
Publication year - 2015
Publication title -
inflammation and cell signaling
Language(s) - English
Resource type - Journals
ISSN - 2330-7803
DOI - 10.14800/ics.648
Subject(s) - oxidative stress , obesity , medicine , renal injury , kidney
The mechanisms linking obesity to kidney damage are unknown. The kidney is a target organ for lesions caused by AGEs. The receptor of AGEs (RAGE) has proinflammatory stimuli and appears to play a role in the pathogenesis of renal disease. Thus, treatment with antioxidants can be beneficial for the prevention and therapy of oxidative stress and inflammation in the kidneys resulting from obesity.
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