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Malignant cancer is a serious threat to the health of men and women worldwide, yet no single or combine treatment strategy exists that can effectively eliminate this disease. Recent years, significant interest has been generated in targeting immune system of cancer patients for therapeutic and preventive purposes. Among the several components of immune system, chemokines and cytokines are key potential targets for immunotherapy of cancer. This review provides a brief overview of the current knowledge and recent updates on the use of cytokines or chemokines in cancer therapy and management.

A therapeutic perspective of cytokines in tumor management