Salivary heat shock proteins and their interactions with oral microenvironment | Zendy

Shailja Chatterjee | Zendy; S G Damle | Zendy; Anil Kumar Sharma | Zendy

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Salivary heat shock proteins and their interactions with oral microenvironment

Author(s) -

Shailja Chatterjee,

S G Damle,

Anil Kumar Sharma

Publication year - 2014

Publication title -

inflammation and cell signaling

Language(s) - English

Resource type - Journals

ISSN - 2330-7803

DOI - 10.14800/ics.101

Subject(s) - heat shock protein , salivary proteins , shock (circulatory) , saliva , heat shock , medicine , chemistry , cancer research , biochemistry , gene

Salivary proteomics is an intriguing area of immunobiological interactions. Heat shock proteins are uniquely conserved molecules that maintain high percentage of homology in all species. These proteins mainly act by inducing antiapoptotic and immunoregulatory mechanisms in intra- as well as extracellular milieu. They have been proposed to play an important role in saliva by maintenance of microbiological population. Their contributory protective role in cancer biology is an interesting area of research having immense implications in therapeutics.

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