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Salivary proteomics is an intriguing area of immunobiological interactions. Heat shock proteins are uniquely conserved molecules that maintain high percentage of homology in all species. These proteins mainly act by inducing antiapoptotic and immunoregulatory mechanisms in intra- as well as extracellular milieu. They have been proposed to play an important role in saliva by maintenance of microbiological population. Their contributory protective role in cancer biology is an interesting area of research having immense implications in therapeutics.

Salivary heat shock proteins and their interactions with oral microenvironment