Polymeric pharmaceutical forms - the forms of the future
Author(s) -
Tatyana Hristova,
Rumyana Cherkezova,
Neli Koseva,
Violeta Mitova,
K. Troev
Publication year - 2015
Publication title -
scripta scientifica pharmaceutica
Language(s) - English
Resource type - Journals
eISSN - 2367-6000
pISSN - 2367-5500
DOI - 10.14748/ssp.v2i2.1386
Subject(s) - drug , active ingredient , dosage form , solubility , polymer , chemistry , nanotechnology , pharmacology , biochemical engineering , computer science , materials science , medicine , chromatography , organic chemistry , engineering
800x600 Polymers are gaining even more ground as carriers of therapeutic agents because of the potential to modify the properties of clinically proven medicines, which have limited use due to their shortcomings and side effects. Polymeric pharmaceutical systems are able to solve problems such as dose limitation of drug, poor water-solubility and duration of drug action. Polymer-pharmaceutical conjugates enable the improvement of drug localization in target tissue and also to optimize the drug release speed. Of great interest is the development of even cleverer and newer pharmaceutical forms made of polymers of varied reactivity, which allows for their binding with different biologically active substances. Normal 0 21 false false false BG X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri",sans-serif;}
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