Determination of the Presence of Diphtheria Toxin in the Myocardial Tissue of Rabbits and a Female Subject by Using an Immunofluorescent Antibody Method | Zendy

Mehmet Ceyhan | Zendy; Yasemin Özsürekçi | Zendy; Merve Aydin | Zendy; Kamil Can Akçalı | Zendy; Beril Talim | Zendy; Melda Çelik | Zendy; Eda Karadağ Öncel | Zendy; Venhar Gürbüz | Zendy; Ahmet Emre Aycan | Zendy; İlyas Onbaşılar | Zendy; Turan Buzğan | Zendy

Open Access

Determination of the Presence of Diphtheria Toxin in the Myocardial Tissue of Rabbits and a Female Subject by Using an Immunofluorescent Antibody Method

Author(s) -

Mehmet Ceyhan,

Yasemin Özsürekçi,

Merve Aydin,

Kamil Can Akçalı,

Beril Talim,

Melda Çelik,

Eda Karadağ Öncel,

Venhar Gürbüz,

Ahmet Emre Aycan,

İlyas Onbaşılar,

Turan Buzğan

Publication year - 2015

Publication title -

journal of clinical medicine research

Language(s) - English

Resource type - Journals

eISSN - 1918-3011

pISSN - 1918-3003

DOI - 10.14740/jocmr2142w

Subject(s) - diphtheria , diphtheria toxin , medicine , corynebacterium diphtheriae , antibody , monoclonal antibody , immunofluorescence , myocarditis , toxin , pathology , immunology , microbiology and biotechnology , biology , vaccination

Clinical diagnosis of diphtheria is often difficult, in particular in countries where the disease is rarely observed, such as Turkey. In 2011, after 12 years of no recorded diphtheria cases in Turkey, a 34-year-old woman was diagnosed with diphtheria; she later died of myocarditis. In this study, we aimed to demonstrate the diagnostic potential of an immunofluorescent antibody method to determine the presence of diphtheria toxin (DT) in the myocardial cells of DT-injected rabbits and the female subject.

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