Vancomycin Enemas as Adjunctive Therapy for Clostridium difficile Infection | Zendy

Mark Malamood | Zendy; Eric Nellis | Zendy; Adam C. Ehrlich | Zendy; Frank K. Friedenberg | Zendy

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Vancomycin Enemas as Adjunctive Therapy for Clostridium difficile Infection

Author(s) -

Mark Malamood,

Eric Nellis,

Adam C. Ehrlich,

Frank K. Friedenberg

Publication year - 2015

Publication title -

journal of clinical medicine research

Language(s) - English

Resource type - Journals

eISSN - 1918-3011

pISSN - 1918-3003

DOI - 10.14740/jocmr2117w

Subject(s) - medicine , clostridium difficile , metronidazole , concomitant , vancomycin , diarrhea , clinical endpoint , colectomy , mortality rate , gastroenterology , clostridium difficile toxin a , surgery , antibiotics , clinical trial , microbiology and biotechnology , staphylococcus aureus , colorectal cancer , genetics , cancer , bacteria , biology

For severe, complicated Clostridium difficile infection (CDI), concomitant treatment with IV metronidazole and oral vancomycin is usually prescribed. Sometimes vancomycin per rectum (VPR) is added to increase colonic drug delivery. Our purpose was to examine clinical outcomes of patients with CDI treated with VPR and compare results to a matched control group.

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