Assessment of Incidence and Character of Neurologic/Neuropsychiatric Complications in a Group of Patients with Malignant Melanoma Treated with Adjuvant High Dose Interferon | Zendy

Jarmila Prošvicová | Zendy

Open Access

Assessment of Incidence and Character of Neurologic/Neuropsychiatric Complications in a Group of Patients with Malignant Melanoma Treated with Adjuvant High Dose Interferon

Author(s) -

Jarmila Prošvicová

Publication year - 2018

Publication title -

klinicka onkologie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.204

H-Index - 13

eISSN - 1802-5307

pISSN - 0862-495X

DOI - 10.14735/amko2018361

Subject(s) - parkinsonism , medicine , depression (economics) , incidence (geometry) , complication , adjuvant , melanoma , interferon alfa , surgery , gastroenterology , alpha interferon , interferon , immunology , disease , physics , optics , economics , macroeconomics , cancer research

Authors describe the incidence and character of neurologic and neuropsychiatric complications - particularly depression and parkinsonism - during adjuvant treatment of malignant melanoma (MM) with high dose interferon (HDI). Among the most frequently observed side effects are fatigue, hematotoxicity, and hepatotoxicity. Most research has been directed at depression and parkinsonism because of the lack of literature concerning these complications. Interferon induced parkinsonism has only been described rarely and only in case reports.

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