Luminescent imaging technology as an opportunity to reduce and refine animal experiments: light at the end of the tunnel? | Zendy

Ina Hagelschuer | Zendy

Open Access

Luminescent imaging technology as an opportunity to reduce and refine animal experiments: light at the end of the tunnel?

Author(s) -

Ina Hagelschuer

Publication year - 2009

Publication title -

altex

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.975

H-Index - 51

eISSN - 1868-8551

pISSN - 1868-596X

DOI - 10.14573/altex.2009.3.177

Subject(s) - animal welfare , computer science , imaging technology , luminescence , data science , risk analysis (engineering) , nanotechnology , business , ecology , materials science , remote sensing , biology , optoelectronics , geology

In vivo luminescent imaging technology was introduced in experimental life science research several years ago and has rapidly gained wide acceptance. By making use of this technology substantially more information can be gained from animal experiments than was previously possible. The concept of the 3Rs describes the aim to Refine, Reduce and Replace animal models in research. The goal of the present paper is to systematically investigate the impact of luminescent imaging on the 3Rs. In particular, three examples of applications are explained in detail so as to be accessible to the reader unfamiliar with the procedure. The examples are subsequently analysed for and categorised according to their concrete effect on animal welfare as defined by the 3Rs.

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