Classic Wilms tumor with raised alpha-fetoprotein levels: A case report and literature review

Tumor markers have become important in the armamentarium of diagnostic and prognostic tools in the field of oncology. With advances in the scientific research they have created a place in the management protocols of various tumors. Alpha-fetoprotein (AFP) is one such tumor marker which is known to be elevated in liver tumors and germ cell tumors, especially those with the yolk sac elements. However, there are only a few reports describing elevated AFP levels in Wilms’ tumor, the second most common primary intra-abdominal malignant tumor in children. We present a case of classic Wilms’ tumor with raised AFP levels which followed the trend of treatment.