Multifunction Carbon Implants in Surgical Treatmentof Inflammatory Spinal Diseases

Objective. To analyze results of preclinical tests and clinical application of new carbon implants for fusion in patients with spinal tuberculosis and osteomyelitis. Material and Methods. Experimental and clinical study was performed to assess the opportunity of application of new carbon implants produced by nanomolecular synthesis for anterior fusion in inflammatory spinal diseases. Results. The implants have high strength, maintain the achieved kyphosis correction, prevent postoperative deformity increase, promote union of bone grafts and preclude their resorption and fracture. Application of the implant as a drug delivery depot provides the maintenance of therapeutic antibiotic concentration directly in the fusion zone without adverse effects during four weeks. Conclusion. The performed study is the first stage of investigation into the properties of carbon nanomaterials used in spine surgery. Manufacturing of such implants with not only predetermined shape and porosity but also with controlled drug adsorption and desorption is rather promising. и карбидных материалов.