Ultrasound-assisted Synthesis of Some New Curcumin Analogs and Their Corresponding Pyrazoline Derivatives

In this work, a series of  new  curcumin mono-carbonyl analogs containing benzyloxy moieties and their pyrazoline derivatives were synthesized using a green method (ultrasound assisted technique) along with traditional method.  The work also includes a comparison between the two methods together and with literature.  Remarkable improvements were achieved by dropping down the reaction time from hours to minutes and obtaining higher yields of the products.