Diagnosis of medullary thyroid cancer and prognostic factors of disease aggressiveness | Zendy

Д О Газизова | Zendy; D. G. Beltsevich | Zendy; Anatoliy Tiulpakov | Zendy; Т В Солдатова | Zendy; А V Ilyin | Zendy

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Diagnosis of medullary thyroid cancer and prognostic factors of disease aggressiveness

Author(s) -

Д О Газизова,

D. G. Beltsevich,

Anatoliy Tiulpakov,

Т В Солдатова,

А V Ilyin

Publication year - 2013

Publication title -

endocrine surgery

Language(s) - English

Resource type - Journals

eISSN - 2310-3965

pISSN - 2306-3513

DOI - 10.14341/serg201344-13

Subject(s) - medullary thyroid cancer , medicine , medullary cavity , calcitonin , oncology , thyroid cancer , pathology , disease , basal (medicine) , thyroid , mutation , thyroid carcinoma , gene , genetics , biology , insulin

In the study were enrolled 137 patients with medullary thyroid cancer (MTC). Low 35%-sensitivity of FNAC and high accuracy of basal calcitonin in MTC diagnostics were found. Mutation analysis of the RET pro- tooncogene in familial and sporadic MTC, RAS -gene in sporadic MTC were done. The correlation between type of the mutation and disease aggressiveness was found.

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