Open AccessMarkers for hepatic autoimmune disorders in patients with type 1 diabetes mellitus
Author(s) -
O. S. Derevyanko,
Деревянко Ольга Сергеевна,
Nadejda Sergeevna Dalantaeva,
Далантаева Надежда Сергеевна,
О Н Иванова,
Иванова Ольга Николаевна,
Н. П. Гончаров,
Гончаров Николай Петрович,
Tatiana Vasil'evikonova,
Никонова Татьяна Васильевна,
Olga Mikhailovna Smirnova,
Смирнова Ольга Михайловна
Publication year - 2014
Publication title -
diabetes mellitus
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/dm2014129-33
Subject(s) - medicine , asymptomatic , type 1 diabetes , autoimmune hepatitis , autoantibody , diabetes mellitus , gastroenterology , hepatitis , immunology , antibody , endocrinology
Aim. To assess the occurrence of autoantibodies characteristic of autoimmune hepatitis in patients with type 1 diabetes mellitus (T1DM), and to analyze clinical features of positive subjects. Materials and Methods. . 84 patients (39 male, 45 female) with T1DM were subdivided into two groups and underwent biochemical, immunologic and instrumental examination. Results. Markers for hepatic autoimmune disorders were found to be highly prevalent in patients with T1DM, even in those asymptomatic according to clinical and instrumental diagnostic methods. Conclusion. Our data suggests that T1DM patients are at higher risk of corresponding, though possibly asymptomatic autoimmune disorders.
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