Metastatic Gastric Signet Ring Cell Carcinoma Mimicking Crohnʼs Disease | Zendy

Michael Winter | Zendy; Amr Dokmak | Zendy; Zachary Marnoy | Zendy; Shweta Sinagare | Zendy; Alexander N. Levy | Zendy

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Metastatic Gastric Signet Ring Cell Carcinoma Mimicking Crohnʼs Disease

Author(s) -

Michael Winter,

Amr Dokmak,

Zachary Marnoy,

Shweta Sinagare,

Alexander N. Levy

Publication year - 2018

Publication title -

acg case reports journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.112

H-Index - 4

ISSN - 2326-3253

DOI - 10.14309/crj.2018.36

Subject(s) - medicine , signet ring cell , signet ring cell carcinoma , malignancy , adenocarcinoma , gastroenterology , crohn's disease , mucin , stomach , bowel obstruction , pathology , disease , cancer , radiology

Signet-ring cell carcinoma (SRCC) is an adenocarcinoma characterized by mucin-producing cells and most commonly arises in the stomach. Colonic SRCC can share features of colitis, including long segments of concentric bowel wall thickening and ulcerated mucosa with regions of sparing. We describe a rare case of metastatic gastric SRCC mimicking Crohn's disease. Our patient underwent 2 colonoscopies, and biopsies revealed chronic active inflammation with no evidence of malignancy. The diagnosis of SRCC was only made after colectomy was performed for recurrent bowel obstruction.

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