Posttransplant Lymphoproliferative Disorder Isolated to the Adrenal Gland in a Liver Transplant Patient | Zendy

Tahereh Ghaziani | Zendy; Joy Liu | Zendy; Z. Gordon Jiang | Zendy; Imad Nasser | Zendy; Khalid Khwaja | Zendy; Robert A. Fisher | Zendy; Myrhas | Zendy; Michael P. Curry | Zendy

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Posttransplant Lymphoproliferative Disorder Isolated to the Adrenal Gland in a Liver Transplant Patient

Author(s) -

Tahereh Ghaziani,

Joy Liu,

Z. Gordon Jiang,

Imad Nasser,

Khalid Khwaja,

Robert A. Fisher,

Myrhas,

Michael P. Curry

Publication year - 2018

Publication title -

acg case reports journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.112

H-Index - 4

ISSN - 2326-3253

DOI - 10.14309/crj.2018.10

Subject(s) - medicine , immunosuppression , post transplant lymphoproliferative disorder , lymphoproliferative disorders , rituximab , presentation (obstetrics) , population , complication , pathogenesis , organ transplantation , liver transplantation , adrenal gland , incidence (geometry) , immunology , pathology , lymphoma , gastroenterology , transplantation , surgery , physics , environmental health , optics

Posttransplant lymphoproliferative disorder (PTLD) is a serious complication that accounts for up to 20% of malignancies after solid organ transplantation. We describe a rare case of isolated PTLD in the adrenal gland occurring 7 months after liver transplant in a patient who developed a primary Epstein-Barr virus infection. He was treated with rituximab and his immunosuppression regimen was minimized. We review the incidence, pathogenesis, presentation, and management of PTLD in the liver-transplant population. Our case highlights the variation in the presentation of PTLD and the importance of a high index of suspicion among the at-risk group.

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