Collagenous Gastritis and Helicobacter pylori Infection: A Mere Coincidence?
Author(s) -
Daniela Guerrero Vinsard,
Lady Katherine Mejía Pérez,
Aziza Nassar,
Maria I. Vazquez Roque
Publication year - 2017
Publication title -
acg case reports journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.112
H-Index - 4
ISSN - 2326-3253
DOI - 10.14309/crj.2017.69
Subject(s) - medicine , gastritis , helicobacter pylori , proinflammatory cytokine , esophagogastroduodenoscopy , inflammation , helicobacter , gastroenterology , iron deficiency anemia , atrophy , pathology , diarrhea , histopathology , endoscopy , anemia
A 21-year-old woman presented to our clinic after 7 years of abdominal pain, diarrhea, and iron-deficiency anemia. Initial upper endoscopy revealed severe inflammation and nodularity of the gastric body and active infection. After eradication therapy, esophagogastroduodenoscopy showed gastric atrophy with nodularity resolution. Histopathology revealed scattered plasma cells, eosinophils, and collagen deposition suggestive of collagenous gastritis. can induce proinflammatory cytokines, resulting in fibroblast upregulation. Collagenous gastritis may be caused by an inflammatory response associated with type I, II, and III collagen. Although further research is warranted, we hypothesize that chronic inflammation from may lead to collagenous gastritis.
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