Tubulointerstitial Nephritis as the Initial Presentation of Crohn's Disease and Successful Treatment with Infliximab | Zendy

Brielle Stanton | Zendy; Tiffany Caza | Zendy; Dongmei Huang | Zendy; Mirza Beg | Zendy

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Tubulointerstitial Nephritis as the Initial Presentation of Crohn's Disease and Successful Treatment with Infliximab

Author(s) -

Brielle Stanton,

Tiffany Caza,

Dongmei Huang,

Mirza Beg

Publication year - 2017

Publication title -

acg case reports journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.112

H-Index - 4

ISSN - 2326-3253

DOI - 10.14309/crj.2017.24

Subject(s) - medicine , infliximab , nephritis , differential diagnosis , presentation (obstetrics) , disease , inflammatory bowel disease , crohn's disease , gastroenterology , immunology , pathology , surgery

Tubulointerstitial nephritis (TIN) is not commonly associated in aminosalicylate-naïve patients with Crohn's disease (CD). Our case describes the initial presentation, diagnosis, and management of an adolescent presenting with TIN and underlying CD. Our case emphasizes that CD should be considered in the differential diagnosis of interstitial nephritis as not only a medication-related effect, but also as an extraintestinal manifestation of CD. We also describe successful management of undiagnosed recurring and symptomatic CD-related TIN with infliximab.

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