Ruptured Gastric Aneurysm in α-1 Antitrypsin Deficiency | Zendy

Veeravich Jaruvongvanich | Zendy; Ittikorn Spanuchart | Zendy; Scott T. Gallacher | Zendy

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Ruptured Gastric Aneurysm in α-1 Antitrypsin Deficiency

Author(s) -

Veeravich Jaruvongvanich,

Ittikorn Spanuchart,

Scott T. Gallacher

Publication year - 2016

Publication title -

acg case reports journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.112

H-Index - 4

ISSN - 2326-3253

DOI - 10.14309/crj.2016.91

Subject(s) - medicine , extravasation , epigastric pain , complication , aneurysm , hemoperitoneum , angiography , hematoma , radiology , abdominal aortic aneurysm , surgery , pathology , vomiting

We present a unique vascular complication of α-1 antitrypsin deficiency (AATD) in a patient with an acute onset of epigastric pain and hemodynamic instability. Abdominal computed tomography angiography detected hemoperitoneum and hematoma within the gastrohepatic ligament with active extravasation. Abdominal angiography revealed left gastric aneurysms. An association between AATD and vascular aneurysms has been suggested to be secondary to unopposed proteolytic activity against arterial structural proteins. The aneurysm formation in aortic, superior mesenteric, inferior mesenteric, and splenic arteries has been reported. We report the first case with ruptured gastric artery aneurysm as a complication of AATD.

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