Evaluation of Brain Diffusion Tensor Imaging Parameters and Effectivity in Children with Autism

There are studies showing that social and communicative disorders are related to abnormalities in limbic structures in cases with autism spectrum disorders (3, 4). Limbic system structures such as cingulate gyrus and orbitofrontal cortex contribute to the development of individuals’ self-awareness and capacity to understand others’ behavior (5, 6). Amygdala and hippocampus are involved in the storage of memory related to emotional events, facial recognition and processing of visual cues (7). In this respect, it is thought that these regions play an important role on social, cognitive and effective functions in patients with ASD. In addition, there are a number of structural and functional neuroimaging studies showing that early social disorders of autism are associated with abnormalities detected in certain regions of the frontal lobe responsible for social-cognitive communication (8, 9).