Leflunomide-Induced Peripheral Neuropathy in a Patient with Rheumatoid Arthritis | Zendy

Saliha Eroğlu Demir | Zendy; Kevser Gümüşsu | Zendy; Emine Poyraz | Zendy; Ebru Aytekin | Zendy; Mustafa Güler | Zendy

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Leflunomide-Induced Peripheral Neuropathy in a Patient with Rheumatoid Arthritis

Author(s) -

Saliha Eroğlu Demir,

Kevser Gümüşsu,

Emine Poyraz,

Ebru Aytekin,

Mustafa Güler

Publication year - 2015

Publication title -

bezmialem science

Language(s) - English

Resource type - Journals

ISSN - 2148-2373

DOI - 10.14235/bs.2014.365

Subject(s) - medicine , leflunomide , rheumatoid arthritis , peripheral neuropathy , peripheral , dermatology , diabetes mellitus , endocrinology

Leflunomide has been reported to be associated with the development of peripheral neuropathy in patients with rheumatoid arthritis. However, it is possible that this side effect has been underreported and underrecognized. We reported a case of leflunomide-induced peripheral neuropathy with the aim of raising awareness of this side effect. It was reported that cessation of leflunomide within 30 days of the arising symptoms enhances the likelihood of improvement or complete recovery. We should be aware of the possibility of peripheral neuropathy in patients using leflunomide. Early detection of symptoms and drug discontinuation may permit recovery.

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