Measurement of Impedance Values of Different Erythrocyte Suspensions

Aggregation give rise to erythrocyte surfaces parallel to each other and clustering in a special way. Erythrocyte aggregation occurs only in the suspension phase in the presence of a certain size and structure of macromolecules. This clustering does not occur when the same cells suspended in simple salt solutions. Factors affecting red blood cell (RBC) aggregation can be divided into intrinsic and extrinsic factors: (1) Extrinsic factors include levels of plasma proteins [exempli gratia (e.g.), fibrinogen, macroglobulins], hematocrit and shear rate; (2) Intrinsic factors include RBC shape, deformability and membrane surface properties (1-3)