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The Quantity And Quality Of Worldwide New Drug Introductions, 1982–2003
Author(s) -
Henry G. Grabowski,
Y. Richard Wang
Publication year - 2006
Publication title -
health affairs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.837
H-Index - 178
eISSN - 2694-233X
pISSN - 0278-2715
DOI - 10.1377/hlthaff.25.2.452
Subject(s) - orphan drug , microbiology and biotechnology , world class , quality (philosophy) , agricultural economics , business , economic growth , biology , economics , engineering , bioinformatics , philosophy , epistemology , industrial engineering
We examined trends in the introduction of new chemical entities (NCEs) worldwide from 1982 through 2003. Although annual introductions of NCEs decreased over time, introductions of high-quality NCEs (that is, global and first-in-class NCEs) increased moderately. Both biotech and orphan products enjoyed tremendous growth, especially for cancer treatment. Country-level analyses for 1993-2003 indicate that U.S. firms overtook their European counterparts in innovative performance or the introduction of first-in-class, biotech, and orphan products. The United States also became the leading market for first launch.

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