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Precision Medicine: From Science To Value
Author(s) -
Geoffrey S. Ginsburg,
Kathryn A. Phillips
Publication year - 2018
Publication title -
health affairs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.837
H-Index - 178
eISSN - 2694-233X
pISSN - 0278-2715
DOI - 10.1377/hlthaff.2017.1624
Subject(s) - precision medicine , health care , context (archaeology) , analytics , biomedicine , stakeholder , data science , systems medicine , intersection (aeronautics) , medicine , computer science , systems biology , public relations , bioinformatics , political science , engineering , pathology , law , biology , paleontology , aerospace engineering
Precision medicine is making an impact on patients, health care delivery systems, and research participants in ways that were only imagined fifteen years ago when the human genome was first sequenced. Discovery of disease-causing and drug-response genetic variants has accelerated, while adoption into clinical medicine has lagged. We define precision medicine and the stakeholder community required to enable its integration into research and health care. We explore the intersection of data science, analytics, and precision medicine in the formation of health systems that carry out research in the context of clinical care and that optimize the tools and information used to deliver improved patient outcomes. We provide examples of real-world impact and conclude with a policy and economic agenda necessary for the adoption of this new paradigm of health care both in the United States and globally.

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